8. However, our findings clarified a new S1P-mediated signaling pathway, different from the one mediated by LPA. We found that S1P-induced VEGF-C expression was dependent on the MMP-2, FGF-1 ...

Sphingosine 1-phosphate (S1P) is a biologically active lipid that promotes tumour growth, neovascularization and inflammation. It regulates the growth, survival and migration of mammalian cells ...