近期，浙江大学医学院附属邵逸夫医院蔡秀军教授团队在肝癌耐药领域发表了题为《CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1》 的研究性论文，阐述了circRNA参与的晚期肝癌一线靶向治疗药Sorafenib（索拉非尼）的耐药机制。 近期 ...

《Nature Medicine》发表文章首次成功解读了sorafenib的治疗机理：sorafenib处理FLT3-ITD+白血病细胞可诱导IL-15产量增加，此时如果与同种异体的CD8+ T细胞反应协同作用，可延长6种FLT3-ITD+ AML小鼠模型的生存时间。 大约20-25%急性髓系白血病（acute myeloid leukemia，AML）患者 ...

A preliminary study suggested that sorafenib, an oral multikinase inhibitor of the vascular endothelial growth factor receptor, the platelet-derived growth factor receptor, and Raf may be ...

Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the pathogenesis and perpetuation of ...

Association Between a National Insurer’s Pay-for-Performance Program for Oncology and Changes in Prescribing of Evidence-Based Cancer Drugs and Spending We randomly assigned participants (2:3:3) to 3 ...

Desmoid tumors (also referred to as aggressive fibromatosis) are connective tissue neoplasms that can arise in any anatomical location and infiltrate the mesentery, neurovascular structures, and ...

Nine hundred three previously treated patients were randomly assigned to receive sorafenib versus placebo. On demonstration of progression-free survival (PFS) benefit with sorafenib, patients assigned ...

New York, Aug. 26, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Nexavar (sorafenib) - Drug Insight and Market Forecast - 2030" - https://www.reportlinker.com ...

Recent results from the Phase III NRG-RTOG 1112 clinical study showed that the addition of stereotactic body radiotherapy (SBRT) to systemic therapy with sorafenib significantly improved ...

Lenvatinib and sorafenib are recommended as options for treating progressive, locally advanced or metastatic differentiated thyroid cancer (papillary, follicular or Hürthle cell) in adults whose ...