Although the existence of specific transplantation resistance antigens in transplantable tumors has been known for some time, their exact role in primary ... constituents of tissues and sera may be ...

The strong allogeneic response to donor MHC molecules in transplantation and the weak response to tumor antigens represent ... responses to tumor peptides. Some novel approaches have been ...

Antigens produced by tumor cells are known as tumor-specific antigens. They are actually cytosolic protein derivatives. Tumor antigens are promising cancer therapy possibilities because they are ...

From published reports, a prioritized list ranking 75 tumor-associated vaccine antigens by these criteria is presented. Given the large number of potential tumor vaccine antigens, and the general ...

it is necessary to select an appropriate conjugation strategy that optimally presents tumor antigens of interest on VLPs. Currently, various strategies are used in research, but the specific approach ...

for example, checkpoint inhibitors tend to be ineffective. CAR-T cells, engineered to recognize tumor-specific antigens, although successful in some blood cancers and lymphomas, have not been ...

recognizes specific tumor antigens through its chimeric antigen receptor (CAR), leading to enhanced phagocytosis of the tumor cells and concomitant presentation of tumor antigen to T cells for their ...

High levels of the cancer antigen 15-3 (CA 15-3 ... other cells that are responding to cancer — contain or produce. In some cases, certain benign conditions can also lead to the production ...

off-tumor toxicity that have hindered similar therapies in the past. 34 Another example of logic-gated CAR-T cell therapy is the Dual-RevCAR platform, designed for CRC, which targets CEA and EpCAM.

Ovalbumin (OVA) or bovine serum albumin (BSA) was incorporated into AFDs to determine how the addition of these food antigens ...