Smith–Lemli–Opitz syndrome (SLOS) is an autosomal recessive, multiple malformation syndrome due to an inborn error of cholesterol synthesis. The SLOS phenotypic ...

Thurm A, Tierney E, Farmer C, Albert P, Joseph L, Swedo S, Bianconi S, Bukelis I, Wheeler C, Sarphare G, Lanham D, Wassif CA, Porter FD. Development, Behavior, and ...

The children also failed to meet the criteria for a rare genetic condition called Smith-Lemli-Opitz, which hampers brain development in fetuses by disrupting cholesterol production in fetuses.

The hypothesis is that prenatal fentanyl exposure possibly interferes with cholesterol metabolism, leading to findings resembling Smith-Lemli-Opitz syndrome (SLOS) in 10 infants. However ...

Fliesler continues to investigate retinal diseases and degeneration linked to cholesterol processing, such as Smith-Lemli-Opitz syndrome (SLOS), a birth defect resulting in dysmorphic and cognitive ...

The defects were similar to those seen in a genetic condition called Smith-Lemli-Opitz, though no genetic cause was found. The powerful opioid painkiller was the suspected cause of 70,601 overdose ...

The birth defects in the babies closely resemble a rare genetic condition called Smith-Lemli-Opitz. It’s a condition that affects how fetuses make cholesterol, which is critical for the brain to ...

The birth defects in the babies closely resemble a rare genetic condition called Smith-Lemli-Opitz. It’s a condition that affects how fetuses make cholesterol, which is critical for the brain to ...