UMI Small RNA测序，文库构建时引入特异性分子标签（UMI），结合高通量测序，研究某物种某组织在特定时空状态下18-30 nt的small RNA片段序列信息，实现绝对定量，通过与数据库比对, 可实现small RNA序列的鉴定、预测、靶基因分析和功能分析， 以及包含miRNA、siRNA ...

“We want to be able to look at what's going on at the level of the genome.” Because gene expression changes occur in multiple cell types throughout spermatogenesis, their project ended up being huge ...

"95% of human RNA is ribosomal RNA ... The advantage of nanopore sequencing is that it relies on small, portable sequencing devices that can fit in the palm of a hand. Researchers can insert ...

A research team led by Rice University’s Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a ...

These small RNAs can bind to complementary mRNA sequences ... RNA-based diagnostic tools, such as RT-PCR and RNA sequencing, are widely used for detecting and quantifying RNA in biological samples.

Men who experienced abuse or neglect in childhood show distinct changes in the molecular makeup of their sperm, according to ...

A research team led by Rice University's Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses.

Researchers uncover new insights into the molecular mechanisms of ADAR1, a protein that regulates RNA-induced immune responses. Their findings could open new pathways for treating autoimmune diseases ...