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另一方面,研究者们对于白血病患者的牛磺酸摄入表达了担忧。这项研究的数据表明额外补充牛磺酸可以加速小鼠模型中白血病的进展。牛磺酸是能量饮料中的常见成分,在一些医疗机构还会被推荐作为减轻化疗副作用的补充剂。现在看来,白血病患者或许需要对摄入牛磺酸更加谨慎了。
近期在顶级学术期刊《自然》(Nature)上发表的一篇论文可能会让很多人感到不安,因为文章标题中就赫然写着——肿瘤微环境的牛磺酸会促进白血病的进展。论文截图如果你还没有想起牛磺酸是什么,可以留意一下超市或便利店的饮料货架,很多能量饮料的配方中都有牛磺酸的大名。
2024 年 4 月 25 日在《细胞》(Cell)上刊登的一篇标题为《癌症中SLC6A6介导的牛磺酸摄取反式激活免疫检查点基因并诱导CD8+ T细胞耗竭》(Cancer SLC6A6 ...
来自罗切斯特大学医学中心等机构的科学家们通过研究发现了一种名为牛磺酸(Taurine)的非必需氨基酸或在白血病的发生和发展中扮演着关键角色 ...
亚群扩增最显著。互作网络预测这些细胞通过牛磺酸-slc6a6轴与lscs通讯。 2. 牛磺酸的代谢劫持机制 crispr筛选显示taut缺失使lscs凋亡率升高5倍,而正常造血祖细胞不受影响。
US researchers have found that taurine, an amino acid often added to energy drinks such as Red Bull and Celsius, can act as a fuel source for leukemia cancer cells, which develop in bone marrow.
In addition, it was found that leukemia cells use the taurine transporter (SLC6A6) to deplete taurine from the bone marrow and promote their own glucose breakdown (glycolysis), which is reported ...
The new study looked at mice with a SLC6A6 gene, which transports taurine from different areas of the body. They also took samples of human leukemia cells and transplanted them into the mice.
A study shows that leukemia cells drink up taurine, which is produced in the body and also consumed through foods and in energy drinks, and use it as fuel for growth. This highlights a potential ...
Researchers at the University of Rochester’s Wilmot Cancer Institute found that taurine, an ingredient in energy drinks like Red Bull and Celsius, could increase the risk of blood cancers ...
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