UB researchers have uncovered how heat causes a critical receptor protein within cells to unfold and relay pain.

Next time you feel an itch, remember that your brain's vast network of neurons informs it whether it is an itch or pain. A ...

Researchers found that a pain receptor called TRPA1 becomes ... In humans, this receptor can induce eye and skin irritation. In mosquitoes, it influences which hosts the insects find most alluring ...

They’ve focused particularly on TRPV1, a receptor found at the endings of peripheral nerves in the skin that’s integral to detecting temperature and pain and also responds to capsaicin, the component ...

Hotter temperatures may render natural insect repellents less effective against mosquitoes, according to a new study.

The McDougall Lab has identified PAR-2 and PAR-4 in joint tissues. Activation of these receptors sensitizes joint nerves leading to the generation of pain and inflammation. We have also found that ...

Furthermore, group I mGluR antagonists not only prevent, but also attenuate established formalin-induced pain ... of glutamate receptors in unmyelinated axons of rat glabrous skin.

Citation: Bitter taste receptors in skin cells function as a defense mechanism against harmful substances, researcher discover (2025, February 25) retrieved 25 March 2025 from https://phys.org ...