Single-Stranded DNA The molecule of the hereditary material deoxyribonucleic acid (DNA) normally consists of two interwoven strands. The discovery of a form with only one strand promises to ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

Recently, Professor Frédéric Veyrier at the Institut national de la recherche scientifique (INRS) and his team developed a new genetic tool based on a family of specific enzymes called Ssn that allows ...

First, they fabricated a universal single-strand DNA, as well as library of hundreds of short, single DNA strands called bricks. Each brick is composed of 24 nucleotides, including cytosine sites ...

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...

The team initially set out to study another replication machinery protein, single-stranded DNA-binding protein, and its interaction with DNA polymerase. However, they first needed to establish how the ...

More information: Haichao Zhao et al, Distinct regulation of ATM signaling by DNA single-strand breaks and APE1, Nature Communications (2024). DOI: 10.1038/s41467-024-50836-6 Journal information ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the ...