For the gene expression study, led by the Allen Institute’s Hongkui Zeng, researchers performed single-cell RNA sequencing on more than 20,000 cells, most of which were neurons, in the visual cortex ...

We pursue the development of novel single cell methods for characterizing genomic, epigenetic and transcriptional variations at single cell resolution. We use genetically engineered mice models to ...

Her favorite projects involve sharing the insights of science and medicine. View Full Profile. Learn about our Editorial Policies. The first single-cell analysis of the human ovarian cortex revealed ...

One reason why ... changes in the mice. "MAPT Int10+3G>A and MAPT S305N;Int10+3G>A lines show abundant hyperphosphorylated tau in the hippocampus and entorhinal cortex, but they do not develop ...