The hierarchical shotgun sequencing strategy involves several steps. First, a library is created by fragmenting the target genome and cloning it into vectors. Next, the genomic DNA fragments are ...

Figure 1 shows the exponential increase in DNA sequence information deposited in the High-Throughput Genomic Sequences (HTGS) division of GenBank by the end of the shotgun phase. Indeed ...

Since The Institute for Genomic Research first decoded the complete genetic material of a free-living organism (Haemophilus influenzae) in 1995 ... system that streamlines critical sample preparation ...