Named after shotgun DNA sequencing, in which long DNA sequences are computationally reconstructed from many short sequencing reads, shotgun proteomics identifies proteins from tandem mass spectra ...

The shotgun phase of the Human Genome Project itself consisted of three steps: Obtaining a DNA clone to sequence Sequencing the DNA clone Assembling sequence data from multiple clones to determine ...

Shotgun sequencing instead takes a genome-wide approach, targeting random sections of bacterial DNA and matching the resulting profile to a database using common sequences or clade-specific marker ...