thereby potentially interfering with an important servomechanism regulating appetite. A PAM targeting this receptor could also potentially correct the negative impact of cholesterol on CCK1R function.

Campbell, F. W., and Robson, J. G. (unpublished experiments). Baker, F., Emmerich, G. W., Tyler, V., and Stark, L. (unpublished experiments).

Xu Jian, chief engineer of the project, said the artificial heart works like a rocket's servomechanism, which is driven by a hydraulic pump. A servomechanism uses feedback to control an operation.