The recognition of the serrated neoplasia pathway represents a major paradigm shift in our understanding of colon carcinogenesis. Although the serrated neoplasia pathway is well established ...

"Not all colon polyps are cancerous but all colon cancer starts as a polyp which ... more often than the standard every 10 ...

And it's attempting to address two pathways by which colon cancer initiates,” said Nilay Sethi ... for studies like this one that shed light on the molecular details of how serrated adenomas form and ...

Aspirin use in patients with PI3K-mutated colorectal cancer helped to reduce disease recurrence, highlighting the importance ...

Approximately 30% of colorectal cancers arise via the serrated neoplasia pathway. Serrated polyps are morphologically, histologically and molecularly distinct from conventional adenomas.