The recognition of the serrated neoplasia pathway represents a major paradigm shift in our understanding of colon carcinogenesis. Although the serrated neoplasia pathway is well established ...

Approximately 30% of colorectal cancers arise via the serrated neoplasia pathway. Serrated polyps are morphologically, histologically and molecularly distinct from conventional adenomas.

And it's attempting to address two pathways by which colon cancer initiates,” said Nilay Sethi, a cancer biologist at the Dana-Farber Cancer Institute who was not involved in the study. Sethi ...