We now know that the segregation of genes occurs during meiosis in eukaryotes, which is a process that produces reproductive cells called gametes.

This figure depicts chromosome segregation errors in meiosis. (A) The three main classes of segregation errors. (B) Incorrect alignment of chromosome kinetochores (C) Mitotic spindle errors.

During meiosis, sister chromatids produced by chromosome duplication are held together by Rec8, a meiosis-specific cohesion protein. Rec8 joins the whole length of the sister chromatids together ...

Meiosis reduces ploidy by following one round of DNA replication with two rounds of chromosome segregation (Meiosis I and Meiosis II respectively). In Meiosis I homologous chromosomes separate, which ...

Unlike its DNA repair role in somatic cells, homologous recombination has a distinct role in meiosis in ensuring proper chromosome segregation. In yeast, an early step of the meiotic program is the ...

But their accumulation in the populations of Madeira Island and in multiple other isolated mouse populations elsewhere is likely due to another influencing factor: the preferential segregation of the ...

For example, in hybrid yellow monkeyflowers (Mimulus guttas x M. nasutus), the “distorter locus” (D) exhibits a whopping 98:2 segregation bias in the seed parent, resulting in an overabundance of DD ...