四价（sp 3 ）碳上的亲核取代反应（Nucleophilic substitution）是有机合成中的一种基本转化，对于构建碳 - 碳和碳 - 杂原子键至关重要。虽然双分子亲核取代反应（S N 2 反应）的机制已被充分理解，但由于连续碳正离子中间体的复杂性，在单分子亲核取代反应（S N 1 ...

Bateman, L. C., and Hughes, E. D., J. Chem. Soc., 945 (1940). Hughes, E. D., Ingold, C. K., and Taher, N. A., J. Chem. Soc., 949 (1940). Berliner, E., and Monack ...

In undergraduate organic chemistry courses, nucleophilic substitution reactions are often carried out as an experiment. Reactions that occur at saturated carbons are chiefly categorized as S N 1 or S ...

Let’s talk about Nucleophilic substitution reaction. The detail about the reaction mechanism and how the complete reaction takes place, you have already studied and this not the time to give you ...