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ACSS2 调控衰老新机制:开启衰老相关疾病治疗新方向
为探究 ACSS2 对细胞衰老的调控作用,研究人员发现其通过 PAICS 影响嘌呤代谢,或成治疗衰老相关疾病新靶点。 研究人员在这项研究中运用了多种关键技术方法。在细胞实验方面,通过构建多种细胞衰老模型,如 4 - 羟基他莫昔芬激活的致癌 RAS ...
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