Researchers revealed that the rotavirus NSP4 protein drives disease severity by disrupting calcium signaling in infected and nearby cells. These disruptions worsen symptoms and trigger immune ...

Image shows 3D human jejunal intestinal organoid infected with human rotavirus. Red is rotavirus, green is E-cadherin and blue are nuclei. Targeted mutation via reverse engineering answers critical ...

“They are safe for animals and humans, and are easily obtained.” The protein VP6, from the intermediate layer of the rotavirus protein shell, is known to elicit a strong immune response ...

The current focus is on viruses that are causative agents of endemic severe diarrhea in humans. These viruses include rotavirus, calicivirus, and Norwalk virus. Rotavirus is the major pathogen of ...

Certain types of gut bacteria can hinder the efficacy of the rotavirus vaccine, according to researchers at the Institute for ...

Background and aims: Although Rotavirus (RV) infection in newborns is usually asymptomatic, outbreaks have been reported, associated with increased incidence of necrotizing enterocolitis (NEC).