The discovery in the early 1980s that certain RNAs can behave as enzymes that catalyze RNA cleavage and ligation reactions has had a large effect on both basic and applied research. Catalytic RNAs ...

Targeting therapeutics against RNA translation ... PA), as well as Boulder, Colorado–based Ribozyme Pharmaceuticals and its spinoff, Atugen.

"Our findings could therefore provide new directions for the development of RNA-based therapeutics" says Höbartner ... activity of the SAM-utilizing ribozyme SAMURI, Nature Chemical Biology ...