A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...

Researchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular ...

That process led to the group discovering a lasso peptide that exhibited broad-spectrum antibiotic activity and was effective ...

HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...

The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.

When they checked what kinds of proteins it bound to, they found many RNA-binding proteins involved in ribosome assembly. Based on their findings, the scientists hypothesized that cyclophilin A was ...

Enteroviruses such as poliovirus and coxsackievirus shut off cap-dependent protein synthesis (translation) within two hours of infection while allowing cap-independent translation of mRNAs containing ...