The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize the overall structure ... This discovery led to the concept of the ribosome as a ribozyme, an RNA molecule ...
as the ribosome and its subunits represent the largest asymmetric structures solved by X-ray crystallography. Now, for the first time, double stranded RNA helices and the α-helices of ribosomal ...
Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...
The ribosome is a large molecular complex of RNA and protein. When eukaryotic ribosomes are isolated from cell extracts ... The Ribosome Quality Control Complex (RQC) recognizes and destroys ...
Each tRNA molecule has an anticodon that is complementary to a specific codon on the mRNA. The tRNA binds to its corresponding amino acid and transports it to the ribosome, where it is incorporated ...
Researchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ...
Ribosomes are made of proteins and a special type of RNA molecule called ribosomal RNA (rRNA). rRNA molecules are the target of chemical modifications, affecting the ribosome's function.
That process led to the group discovering a lasso peptide that exhibited broad-spectrum antibiotic activity and was effective ...
Further investigation into SNORA13 revealed that it modifies RNA bases in the ribosome’s active site ... 6 Mendell said, “Almost all of the factors that we know that are involved in building ribosomes ...
Free F1000 Evaluation The ribosome was thought to treat all messenger RNAs the same, connecting coded peptides into a protein chain like a mindless machine. However, Maria Barna, a developmental ...