Ribavirin, the nucleoside ... In the enzymatic method, purine nucleoside phosphorylase is used to catalyze ribavirin synthesis from its precursors – purine nucleoside and 2H-1,2,4-triazole-3 ...

A new finding from Poland is the association between serum prohepcidin and PEG-IFN/ribavirin efficacy in chronic hepatitis C, which may suggest possible HCV interference with hepcidin synthesis.

The currently recommended regimen for the treatment of chronic hepatitis C is the combination of weekly subcutaneous injections of peginterferon and twice daily oral doses of ribavirin . 13,28,29 ...

To determine the effect of incorporated ribavirin on subsequent rounds of RNA synthesis, we evaluated the kinetics of CMP and UMP incorporation into sym/sub-R, a template containing ribavirin ...

Clinical pharmacology. Ribavirin is a purine nucleoside analogue. Although its mechanism of action is still debated, it prevents replication of a large number of RNA and DNA viruses by inhibiting the ...

Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) is a purine analogue and a commonly used antiviral agent against both RNA and DNA viruses. With up to five suggested mechanisms of ...