With more than 800 members, GPCRs are one of the most diverse and important groups of human proteins. They are divided into five major families based on structural similarities 1: rhodopsin (class ...

The receptor fold is very similar to that of rhodopsin in its inactive state. The root-mean-square (r.m.s.) deviation between the two structures, which belong to the same subfamily of GPCRs (Class ...

This study makes the fundamental discovery of the first natural animal rhodopsin that uses a chloride ion instead of an amino acid side chain as a counterion. Using a combination of biochemical and ...