Long-lived plasma cells, which produce autoantibodies in diseases such as systemic lupus erythematosus (SLE), are an as yet unexplored therapeutic target in such antibody-mediated disorders.

Idiopathic inflammatory myopathies (IIMs) are associated with autoantibodies against nuclear and cytoplasmic antigens. Myositis-specific autoantibodies (MSAs) are specific to patients with IIMs.

The following is a summary of “Recognition of glycine versus non-glycine citrulline motifs dictates the HLA class II ...

Arthritis & Rheumatism. 2006;54(10):3087-3094. Rheumatoid arthritis (RA), a chronic autoimmune disease marked by tissue inflammation and joint destruction, has a well established ...