Sir Richard Roberts, Chief Scientific Officer at NEB, commented on the announcement, “NEB has a 40-year history innovating in the field of molecular biology enzymes and related technologies. WarmStart ...

Again, the selectivity of the inhibitory activity of AZT for a viral enzyme — HIV reverse transcriptase — compared with enzymes involved in DNA synthesis in normal cells provided a therapeutic ...

Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...

A retroviral enzyme which converts genetic material from RNA into DNA, an essential step in the lifecycle of HIV. Several classes of anti-HIV drugs interfere with this stage of HIV’s life cycle: ...

CRF: Circulating recombinant form; NNRTI: Non-nucleoside reverse-transcriptase inhibitor; NRTI: Nucleos(t)ide analog reverse-transcriptase inhibitor. Eight nucleos(t)ide analog reverse ...

“We’re excited to share these enzymes with the genome editing ... such as deaminase domains for base editors, reverse transcriptase domains for prime editors, and DNA polymerases for click ...

Researchers from Sanford Burnham Prebys have found that HIV-positive individuals treated with reverse transcriptase inhibitors ... could be recombined by enzymes similar to those targeted by ...