Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10 ...
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Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. St. Jude Children’s Research Hospital scientists resolved the mystery, ...
Neuroblastoma, an aggressive malignancy originating from neural crest cells, accounts for 15% of cancer-related deaths in children. Treatment strategies include systemic chemotherapy, radiation or ...
For nearly 50 years, doctors have known that the drug retinoic acid helps treat neuroblastoma, a type of solid tumor that ...
When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10-15%. However, this effect was only evident in post ...
Retinoic acid (RA) is one of several molecules that pattern vertebrate embryos by forming an anterior to posterior (A–P) concentration gradient. The issue of whether RA is a classical morphogen ...
Topical retinoids (for example, tretinoin) and retinoid analogues (for example, adapalene and tazarotene) help normalize hyperkeratinization and have demonstrated significant anti-inflammatory ...
YourChoice Therapeutics, Inc., pioneering hormone-free family planning products, announced today that Communications Medicine, a Nature Portfolio journal, has published a peer-reviewed paper on the ...
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