According to current concepts of renal physiology ... leaving osmotically free water in the tubule for excretion. The large increase in isosmotic solute excretion that follows hydrochlorothiazide ...

It adjusts urinary excretion of phosphate according to ... by the glomerulus occurs almost exclusively in the renal proximal tubule and is an active, hormonally regulated process.

The renal tubule is a long and convoluted structure ... depending on the substance being moved and other conditions. Excretion is the net sum of filtered – (reabsorbed and secreted).

"The proximal renal tubules seem to be a specific target of ... we believe that the four markers (increased urinary excretion of protein, phosphate, uric acid and glucose), if a new occurrence ...

Un-ionized drugs and metabolites are usually able to diffuse out of the renal tubule and are reabsorbed into the blood. Urine pH can alter reabsorption and excretion due to the effect that it has ...

In mice, a consistent phosphorus-rich diet increases phosphate concentration in the proximal tubule fluid of the kidney. Increased phosphate excretion has been associated with tubular damage and ...

These basic functions are critical to regulation of fluid and electrolyte balance, body fluid osmolality, acid-based balance, excretion ... of the proximal tubule. 13 Renal release of glucose ...

A right kidney stone as seen on abdominal ... increase re-absorption of calcium in the distal tubules, thereby decreasing urinary calcium excretion; allopurinol, a xanthine oxidase inhibitor ...

Efficient proximal tubule-on-chip model from hiPSC-derived kidney organoids for functional analysis of renal transporters. iScience , 2024; 27 (9): 110760 DOI: 10.1016/j.isci.2024.110760 Cite This ...

A reduction in urinary citrate levels may be the mechanism underlying the higher incidence of kidney stones in patients taking PPIs, according to investigators. Individuals who use proton pump ...