Febrile urinary tract infection (fUTI) in children may cause renal scarring. This study aimed to investigate the usefulness of urinary biomarkers for diagnosing renal scarring after fUTI.

Renal scarring was defined by the presence of decreased uptake of labeled dimercaptosuccinic acid associated with loss of the contours of the kidney or by the presence of cortical thinning with ...

The investigators defined renal scarring as decreased uptake of tracer associated with the loss of contours or cortical thinning on a technetium 99m dimercaptosuccinic acid (DMSA) renal scan ...

At 6 months after treatment, 33.3% of children who received methylprednisolone had renal scarring on DMSA, as did 60.0% of those who received placebo (P < .05), with median cortical defect volumes ...