You may need surgery to remove large or very painful tophi or repair damage from tophi. Most people will never need surgery ...

The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

prevent urate deposition (tophi) in various body tissues and influence the progressive course of chronic tophaceous gout. With accumulating experience in the continuous use of uricosuric agents ...

The previous paragraphs described certain gout scenarios ... If crystal removal from joints and tissues leads to the disappearance of acute attacks and tophi – which may be considered as the ...