Raynaud’s phenomenon is a condition that causes blood vessels in the hands and sometimes the feet to constrict, limiting blood flow to the fingers and toes. This reduced blood flow causes ...

The current treatment options for Raynaud phenomenon are often ineffective and can have undesirable adverse effects. Topical, or transdermal, treatments that increase digital blood flow without ...

According to a 2023 case report, there is a causal relationship between hypothyroidism and Raynaud phenomenon. Raynaud phenomenon is a condition in which the blood vessels in the extremities ...

Scleroderma is a rare disease in which a person's immune system begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result, connective tissue of the skin, lungs, ...

As an orally available inhibitor of endothelin-1, which has been implicated in the pathogenesis of vascular disease in systemic sclerosis (SSc), bosentan is widely used as first-line therapy for ...

Raynaud's disease is a condition that causes parts of your body, like your fingers or toes, to feel cold and numb when you are in cold temperatures or feeling stressed. Raynaud's occurs in 3% to 5 ...