The RNA world hypothesis gains support from the in vitro evolution of a bifunctional ribozyme that can recognize an activated glutaminyl ester and subsequently aminoacylate a tRNA molecule.

Pamela Pavco (Ribozyme Pharmaceuticals Inc ... in which an assessment of safety is the goal. *The RNA World, satellite meeting of the American Society for Biochemistry and Molecular Biology ...

In a paper published today (August 15) in PNAS, scientists from the Scripps Research Institute in La Jolla, California, report on their use of in vitro evolution to generate an improved polymerase ...

A major focus of our lab is to harness the power of small catalytic RNAs (such as the hammerhead ribozyme) to create new RNA switches that can be turned on or off by small molecules. One of the ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

A group of researchers led by Professor Claudia Höbartner at the University of Würburg (JMU) has now uncovered the three-dimensional structure of a very special ribozyme: SAMURI. This is an RNA ...

Imagine a world where proteins could ... a natural preference built into these RNA molecules. Instead, it depends on the specific design or family of the ribozyme. This suggests that life ...