The demonstrated ability of modern DNA-dependent RNA polymerases ... Interestingly, the structure of the L1 ligase ribozyme 14 demonstrates that RNA and protein enzymes use analogous strategies ...

但在监测微生物群落中可移动 DNA 宿主范围时，这些方法的灵敏度存在局限。 为记录废水微生物组中的基因转移信息，研究人员使用合成催化 RNA 对核糖体 RNA（rRNA）的高度保守片段进行条形码标记。通过核酶（ribozyme）将信息写入 rRNA，并利用扩增子测序读取 ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

RNA is often compared to a copy from a reference book, or a template, because it carries the same information as its DNA template but is not used for long-term storage. Each ribonucleotide base ...

"Instead of writing information randomly in bacterial DNA, which is permanent and ... To achieve this, the researchers designed a small ribozyme-based RNA molecule (also called catalytic RNA ...

A major focus of our lab is to harness the power of small catalytic RNAs (such as the hammerhead ribozyme) to create new RNA switches that can be turned on or off by small molecules. One of the ...

RNA is similar to DNA but contains uracil instead of thymine (T ... For example, the ribosome itself is a ribozyme, as the rRNA component catalyzes the formation of peptide bonds during protein ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

For the latest on this threshold to the RNA world, see Kennedy et al (2008) Frontiers in Bioscience 13: 6060-6071. Catalyzed and Spontaneous Reactions on Ribozyme Ribose - Extensive enzymatic product ...

In a paper published today (August 15) in PNAS, scientists from the Scripps Research Institute in La Jolla, California, report on their use of in vitro evolution to generate an improved polymerase ...