There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

EZH1 is a key regulator of circadian rhythms, stabilizing gene transcription and modifying chromatin to maintain genetic ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

This enables the RNA polymerase (RNAP) and the ribosome to coordinate their functions and work together efficiently directly. Bacteria are the most well-understood prokaryotes, and due to their ...

The plan lists six anti-influenza drugs available in China, including oseltamivir, peramivir and zanamivir. It adds ...

A global team has made a significant advance in understanding how bacterial plasmids contribute to antibiotic resistance.

This unwinding of the helix is caused by an enzyme (helicase enzyme). The enzyme RNA polymerase attaches to the DNA in a non-coding region just before the gene. RNA polymerase moves along the DNA ...

Our mission is to elucidate fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in ...