RNA abundance is regulated by balancing transcription and degradation in processes that control the temporal and spatial distribution of cellular RNA. In eukaryotic cells, mRNA decay is catalyzed by ...

A fast and simple protocol for isolating exosomal RNA from exosomes previously purified using Norgen's Exosome Purification Kits, ultracentrifugation, size-exclusion chromatography, or most other ...

ExosomeDx harnesses biological information from exosomes for biomarker discovery and diagnostic development. The company’s pipeline of products includes the ExoDx Prostate test, the first ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

Enter exosomes—tiny biological "messengers" released by cells. These nano-sized bubbles, packed with molecules like proteins and RNA, act as a communication network between cells.

Building on the discovery and characterisation of the exosome ribonuclease complex (Mitchell et al., 1997; Allmang et al., 1999), my lab’s research addresses the molecular mechanisms of RNA quality ...

A functional competition between RNA export factor AlyREF and the RNA exosome adaptor protein ZFC3H1 determines the fate of polyadenylated RNA. Shortly after RNA transcription starts, the nascent ...