The structure of NS5B significantly extends structural studies of RNA-dependent RNA polymerases ... recur in well-characterized polymerases, the atomic details of functionally similar changes ...
“NuFold can help bridge the gap by predicting the 3D structures of RNA from its sequence. By leveraging state-of-the-art machine learning techniques, NuFold can predict the full atomic structure ...
Scientists used atomic force microscopy (AFM ... because they adopt multiple conformations once in solution. No large RNA structure database exists that correlates sequence with 3D topology.
To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, which is made up of eight RNA molecules.