Essentially, 4SC classifies RBC into four shapes that include intermediate states of deformation. This provides a more refined view of RBC deformability compared to only classifying RBCs into two ...

Red blood cells (RBCs) transport oxygen throughout the body and are able to pass through a complex of narrow capillaries due to their ability to deform. “The deformability of RBCs is an ...

Accurate measurement of RBC deformability and adhesion, which are the two key biophysical factors of vaso-occlusion in SCD, holds great potential as a marker for evaluation of disease progression ...

In addition, an interplay between poor cellular deformability and impaired oxygen delivery is found in various pathological processes such as sickle cell disease. Sickle red blood cells ...

Since hemin is difficult to measure directly -- it tends to insert itself into cell membranes -- monitoring changes in RBC deformability can therefore serve as a reliable alternative marker of ...

The biconcave disk shape and deformability of mammalian red blood cells (RBCs) rely upon the membrane skeleton, a viscoelastic network of short actin filaments interconnected by long spectrin ...

TASS/. Students of the Biology Institute of the University of Tyumen have developed a device to measure the deformability of red blood cells, the university’s press service told TASS on Thursday.