Recent research has shown that the formation of highly synapto-/neurotoxic soluble Aβ oligomers is triggered by a specific form of Aβ called pyroglutamate-Aβ (pGlu-Aβ) 1. Probiodrug’s focus ...

The data for LY3002813 will be the first test of the potential for antibodies as a passive immunisation against pyroglutamate- amyloid beta (pGlu-Abeta), a target that relates to but diverges from ...

The Boston biotech said the platform had enabled the development of ALIA-1758 – an anti-pyroglutamate amyloid beta (Aβ3pE) antibody, which it says is a 'potential best-in-class therapy for ...