A new study reveals a possible protein misfolding mechanism that may resolve a long-standing mystery of why certain proteins ...

In 1961 the structure of one protein, myoglobin, was known at 6 Å resolution and its 2 Å structure would soon be published. The structural determinations of hemoglobin and hen lysozyme were well ...

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.

A new study demonstrates a potential protein misfolding mechanism that could solve a decades-old mystery of why some proteins ...

This article explores how automation is transforming proteomics by streamlining proteoform analysis, boosting throughput and ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular ...

James Berger, Karen Fleming, and Gregory Kirk join an esteemed group of scientists, engineers, and innovators who have been ...

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions. This folding process occasionally goes awry, resulting in misfolded ...

A novel protein cage system can control and visualize orientational changes in aromatic side chains upon ligand binding. By inducing coordinated molecular changes, this approach enables precise ...

In the process, DNA is transcribed into RNA and then translated into functional proteins that subsequently undergo folding to ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this gap ...