As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every ...

生态系统的人为干扰正以前所未有的速度重塑病毒传播格局。气候变迁与人类活动双重压力下，人畜共患病毒（zoonotic viruses）的跨物种传播风险持续升级。过去20年间，多种高突变RNA病毒的暴发表明，传统防控体系在预测流行轨迹和阻断传播链方面存在显著短板。究其根源，这些病原体通过快速抗原漂移（antigenic drift）和重组（recombination）等机制，不断突破宿主免疫防线。本研 ...

This finding supports the idea that antigenic peptides are derived from ‘freshly made’ proteins. TAP–GFP motility was also correlated with the transport of MHC class I molecules from the ER ...

Functions of each viral protein are listed in Table 1. Antigenic drift is the process whereby mutations accumulate in viral surface glycoproteins (predominantly hemagglutinin), resulting in ...

The H5N1 avian influenza virus is mutating to evade immune defenses in mammals following prior infection or vaccination.

New computational modeling of avian influenza variants’ immunoprotein interactions – developed by a research team at the University of North Carolina at Charlotte – reveals the H5N1 influenza virus is ...

Christopher Lee, DVM, MPH, DACVPM, explains why early detection and enhanced biosecurity are essential for mitigating the spread of highly pathogenic avian influenza ...