Findings from the new study were published recently in Cancer Research through an article titled, “Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin ...

However, prodrug intervention must be an integral part of the drug design and discovery ... distribution, metabolism, and excretion) with examples of successful prodrugs developed in industry and in ...

Anticancer drugs could be generated at tumors by the reaction of a prodrug with a gold catalyst in a protein scaffold 1. Chang, T.-C., Vong, K., Yamamoto, T. & Tanaka, K. Prodrug activation by gold ...

The prodrug strategy is basically a smart key that has been designed specifically to unlock the door to cancer treatment only when it reaches the correct target. Utilizing this prodrug strategy ...

A research team led by Professor Won Jong Kim of POSTECH's Department of Chemistry has developed a lymph-directed self-immolative nitric oxide prodrug that is readily conjugated to the protein ...

Scientists have dubbed this type of targeted approach a "prodrug" -- a medicine designed to release its payload in a particular area of the body and in no other areas. The Johns Hopkins-discovered ...

UGA researchers combined cisplatin with aspirin in a new single prodrug formulation they call Platin-A, which prevents these negative side effects by reducing inflammation.

This new article publication from Acta Pharmaceutica Sinica B, discusses how branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status ...

Askgene Pharma Inc. has received FDA clearance of its IND application to start a phase I study of ASKG-915, a novel and proprietary anti-PD-1/IL-15 prodrug fusion molecule for the treatment of cancer.