However, prodrug intervention must be an integral part of the drug design and discovery ... distribution, metabolism, and excretion) with examples of successful prodrugs developed in industry and in ...

Anticancer drugs could be generated at tumors by the reaction of a prodrug with a gold catalyst in a protein scaffold 1. Chang, T.-C., Vong, K., Yamamoto, T. & Tanaka, K. Prodrug activation by gold ...

Zhu Guangyu, Associate Professor of Department of Chemistry, City University of Hong Kong (CityU) and his research team have recently developed phorbiplatin, an anti-cancer prodrug that can be ...

The prodrug strategy is basically a smart key that has been designed specifically to unlock the door to cancer treatment only when it reaches the correct target. Utilizing this prodrug strategy ...

Scientists have dubbed this type of targeted approach a "prodrug" -- a medicine designed to release its payload in a particular area of the body and in no other areas. The Johns Hopkins-discovered ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status ...

Askgene Pharma Inc. has received FDA clearance of its IND application to start a phase I study of ASKG-915, a novel and proprietary anti-PD-1/IL-15 prodrug fusion molecule for the treatment of cancer.