Hypertrophic cardiomyopathy (HCM ... they may need additional tests to confirm a diagnosis, such as: The primary goals of treatment for HCM are to manage symptoms, halt or slow down the ...

For children with severe hypertrophic cardiomyopathy caused by gain-of-function RAS/mitogen-activated protein kinase (MAPK) mutations (RASopathy), trametinib reduces mortality and morbidity.