New research from MIT suggests that astrocytes - long considered support cells - may play a key role in the human brain's ...

However, whether and how presynaptic adhesion molecules trans-synaptically regulate the localization and stabilization of postsynaptic neurotransmitter receptors remained largely unclear.

Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

At synapses, signals are sent by presynaptic neurons and received by postsynaptic neurons. At most synapses, communication occurs via chemical messengers -- or neurotransmitters. When an ...

"Given the presynaptic role of synucleins in regulating ... "Consistent with this hypothesis, postsynaptic expression of tetanus toxin light chain, which cleaves synaptobrevin SNAREs, also blocks ...

Each of these levels covers a different scenario that can occur between the presynaptic and postsynaptic cell, such as spatial summation or coincidence potentiation. Using their knowledge of these ...

Dezhi Liao of the University of Minnesota, Minneapolis, noted that tau is enriched in axons and presynaptic terminals in healthy cells, but moves to postsynaptic structures in neurodegenerative ...

It is not yet clear whether presynaptic deficits precede postsynaptic problems, or vice versa. “This is one of the first papers to explore the function of presynaptic tau,” noted Amy Pooler at the ...

At synapses, signals are sent by presynaptic neurons and received by postsynaptic neurons. At most synapses, communication occurs via chemical messengers—or neurotransmitters. When an electrical ...