A group of slow-witted, mutant mice and a protein called RIM1α may provide insight into learning and memory mechanisms. University of Texas Southwestern researchers showed that knockout mice missing ...

Serafini and colleagues provide evidence that neuroligin acts as a trans-neuronal signal to induce presynaptic differentiation at neuron–neuron connections in vitro. To form a synaptic ...

"Loss of either factor severely reduces presynaptic protein expression," wrote the researchers. "Both factors bind directly ...

Parkinson’s disease (PD) is characterized by the presence in post-mortem brains of Lewy bodies with aggregated forms of alpha-synuclein (aSyn), a presynaptic protein that exists as both cytosolic and ...