Another STIM1 domain, the polybasic Lys-rich domain, regulates Orai1 and is separate from opening of Orai1 by SOAR. The Lys domain regulates the activity of Orai1 at negative membrane potentials ...

In a recent study posted to the bioRxiv* preprint server, researchers evaluated the importance of the P681 residue within the furin cleavage site (FCS) of severe acute respiratory syndrome ...