Uncertainty remains over the consequences of removing Aβ plaques from the brains of ... criteria 10 were drawn from the archives of the Neuropathology laboratory at Southampton General Hospital.

All three types of plaque counts were highly correlated with global neuropathology (r=0.80 to 0.89; all p < 0.0001). When Bielschowsky plaques, iC3b plaques, C9 plaques, and global neuropathology ...

Age-related, progressive neuropathology including plaques and tangles. Extracellular Aβ deposits by 6 months in frontal cortex, more extensive by 12 months. No tau pathology at 6 months, but evident ...

Its cardinal pathological features are extracellular β-amyloid (amyloid plaques) and intraneuronal tau aggregates forming neurofibrillary ... This article provides an up-to-date overview of AD ...

A history of military service is associated with a 26% increased risk for amyloid plaque and 10% increased ... greater risk of having amyloid and tau neuropathology (including the interplay ...

Our aging brains collect tangles and sticky plaques that can interfere in our cognition and memory. But some older adults with this neuropathology have more cognitive resilience than others ...

This review focuses on the current knowledge of the pathogenesis of the inflammatory and neurodegenerative elements of the multiple sclerosis plaque. In Panel A, light microscopy reveals myelin ...

Plasma p-tau217 tightly correlated with postmortem plaques and tangles. It also detected early accumulation of both pathologies. P-tau217 measured five years before death predicted future high ...

18, 2022, edition of Proceedings of the National Academy of Sciences. AD is a progressive neurodegenerative disease with complex underlying pathologies, which extend far beyond its characteristic ...

Molecular tangles and plaques are routinely linked to poorer cognitive function and memory in older adults. But some older adults with this neuropathology have more cognitive resilience than others, ...