In the human, the placenta is the predominant route of IgG transfer in the maternal-to-fetal direction; the immune protection provided by maternal antibodies is essential for newborns during the ...

A study in Reproductive and Developmental Medicine links elevated levels of the KLF12 protein to impaired placental ...

The processes involved in placental development are highly regulated to ensure normal growth of the developing fetal tissues and the maintenance of a healthy pregnancy. A unique function of the ...

Abnormal function of the placenta in a pregnancy affected by chorioamnionitis may also negatively affect prenatal lung development, but the exact mechanisms aren't understood.

Maternal smoking during pregnancy associated with methylation signatures across the placental epigenome in genes involved in regulating inflammation, growth signaling, and cardiometabolic outcomes.