Huge, bacteria-eating viruses could be a game-changer for antibiotics that currently struggle to fend off deadly infections.

Jumbo phages use a protein shield to protect their DNA from bacterial attacks. A special handshake controls which molecules ...

Phages are viruses that attack bacteria by injecting their DNA, then usurping bacterial machinery to reproduce. Eventually, ...

Bacteriophages (phages) can devastate bacterial strains that are used in fermentations and bioprocesses. Comparative genomic analyses can be used to streamline the construction of genetic systems ...

In the early and mid-1980s, scientists used phages to express recombinant proteins. The protein was retained inside the virions, so screening required growing viral plaques, creating a stamp of these ...

Complementary discoveries have the potential to enhance treatment options for antibiotic-resistant infections. Researchers at ...

Scientists insert variable DNA sequences coding for their proteins of interest into plasmids that carry a phage coat protein gene, an antibiotic resistance gene, and a packaging signal. Then they ...

This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

If Pnkp and Rnl1 are not present, depletion of the pool of functional tRNA Lys by PrrC blocks phage protein synthesis and arrests the infection before it can spread. However, Pnkp and Rnl1 repair the ...

The Phage Genomics Lab courses ,sponsored by the HHMI Science Education Alliance, offers introductory biology students an authentic research experience. Students isolate novel bacteriophage from the ...

The phage therapy market is experiencing significant growth due to the increasing prevalence of antibiotic-resistant infections and the growing interest in alternative treatments. Advances in ...