Filamentous bacteriophage fd can display multiple copies of foreign peptides in the N-terminal region of its major coat protein pVIII, 2,700 copies of which make up the virus capsid. Here we show ...

Scientists insert variable DNA sequences coding for their proteins of interest into plasmids that carry a phage coat protein gene, an antibiotic resistance gene, and a packaging signal. Then they ...

In a new study, researchers have screened nine heptapeptide sequences from a random peptide library using phage display technology, with S. aureus 6538 as the target bacterium. The work is ...

While Smith and his colleagues’ peptide libraries demonstrated the potential of phage display, the sequences were randomly generated. Scientists did not have control over the amino acid frequencies, ...

Bacteriophages (T4) were modified with anticancer Tyr–Ile–Gly–Ser–Arg (YIGSR) peptides by phage display and injected intraperitoneally. Results & conclusion: Tumor growth was decreased in ...

for their work on phage display of peptides and antibodies. The other half of this year’s prize went to CalTech’s Frances Arnold for her work on directed evolution of enzymes, which can be ...