While Smith and his colleagues’ peptide libraries demonstrated the potential of phage display, the sequences were randomly generated. Scientists did not have control over the amino acid frequencies, ...

Scientists insert variable DNA sequences coding for their proteins of interest into plasmids that carry a phage coat protein gene, an antibiotic resistance gene, and a packaging signal. Then they ...

They took a technique in which viruses are engineered to display bits of proteins like flags on their surface, called phage ...

Phage display remains the most widely used antibody discovery method owing to its versatility, robustness, applicability, and ...

In this issue, Gishizky and coworkers describe yet another use for phage display—a method for mapping protein–protein interactions that is faster than two-hybrid systems and that allows the ...

CHICAGO--(BUSINESS WIRE)--Tango Biosciences, Inc., the premier research partner for custom affinity reagents by phage display, announced Michael Scholle, MS, MBA as Chief Executive Officer ...

Bacteriophages (T4) were modified with anticancer Tyr–Ile–Gly–Ser–Arg (YIGSR) peptides by phage display and injected intraperitoneally. Results & conclusion: Tumor growth was decreased in ...

Smith and Winter’s work on a technique known as phage display was notably used to develop Humira (adalimumab), first approved in 2002 and now used in a range of inflammatory diseases.

Of the 23 fully human mAbs approved so far, 17 are derived from transgenic mice and 6 were developed with phage-display technology. Yeast display has generated a clinical pipeline, but no marketed ...

In this interview, Technology Networks spoke with Dr. Sophie Mayle, Dr. Paul Royle and Dr. John Cardone from Bio-Rad's ...